Organelle transport: dynamic actin tracks for myosin motors

Curr Biol. 2008 Nov 25;18(22):R1066-8. doi: 10.1016/j.cub.2008.09.048.

Abstract

Transport of cargo by molecular motors on microtubule and actin filament tracks is a fundamental property of eukaryotic cells. A new study reports that actin dynamics are required in cells for myosin I and V motor proteins to transport their organelle cargos on actin tracks.

Publication types

  • Comment

MeSH terms

  • Actin Cytoskeleton / metabolism
  • Actin Cytoskeleton / physiology*
  • Animals
  • Anura / metabolism
  • Biological Transport / physiology
  • Melanophores / metabolism
  • Melanophores / ultrastructure
  • Myosin Type I / metabolism
  • Myosin Type I / physiology*
  • Myosin Type V / metabolism
  • Myosin Type V / physiology*
  • Organelles / metabolism*

Substances

  • Myosin Type I
  • Myosin Type V