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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Hem-1, a potential membrane protein, with expression restricted to blood cells.

Overlapping cDNAs 3.8 kb in length containing a long open reading frame were obtained that hybridized exclusively to transcripts from hematopoietic cells. Sequence analysis found eight potential membrane domains and two possible cAMP/cGMP phosphorylation sites. This sequence exhibited no homologies with the EMBL/Genbank nucleic acid, SwissProt or GenPept amino acid data bases. The gene is located at 12q13.1, a region of occasional translocations in hematopoietic neoplasia and a rare folic acid fragile site, Fra 12A.[1]

References

  1. Hem-1, a potential membrane protein, with expression restricted to blood cells. Hromas, R., Collins, S., Raskind, W., Deaven, L., Kaushansky, K. Biochim. Biophys. Acta (1991) [Pubmed]
 
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