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Enders, D. et al.

Dieter Enders, Chuan Wang, Jens X. Liebich,

Organocatalytic asymmetric aza-Michael additions.

The catalytic aza-Michael addition is an important reaction within synthetic organic chemistry, given the significance of the biologically and synthetically interesting products, such as beta-amino acids and beta-lactams. In the last decade organocatalysis emerged as a powerful tool in asymmetric synthesis and had a large impact on the development of asymmetric and catalytic conjugate additions of nitrogen nucleophiles to Michael acceptors. In this review a first summary of the recent rapid progress of asymmetric organocatalyzed aza-Michael reactions is presented.[1]

References

Organocatalytic asymmetric aza-Michael additions. Enders, D., Wang, C., Liebich, J.X. Chemistry (2009) [Pubmed]

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