Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Sipola, P. et al.

Petri Sipola, Marja Hedman, Pekka Jäkälä, Anne-Mari Karjalainen, Keijo Peuhkurinen, Hannu Manninen, Ritva Vanninen,

Prevalence of pulmonary embolism in patients with suspected cardioembolic ischemic stroke.

PURPOSE: Venous thromboemboli can cause both pulmonary embolism (PE) and paradoxical embolism in the presence of a cardiac right-to-left shunt. Our aim was to prospectively assess the prevalence of PE in patients with ischemic stroke with suspected cardiogenic etiology and thereby to clarify the possible role of paradoxical embolism as a cause of ischemic stroke. MATERIALS AND METHODS: Consecutive patients with suspected cardiogenic ischemic stroke (n=113, male/female=76/37, mean age 62±11 y) underwent computed tomography angiography of the pulmonary arteries to assess for the presence of PE as an adjunct to routine computed tomography angiography of the cervicocranial arteries. Transthoracic and transesophageal echocardiography were used to evaluate for patent foramen ovale (PFO) and cardiac defects. RESULTS: PE was found in 4 patients (3.5%). Only 1 patient with PE had symptoms or signs suggestive of PE. None of the patients with PE had intracardiac defects or PFO. In the entire study population, atrial septal defect was detected in 5 (4%) patients and PFO in 13 (12%) patients. CONCLUSIONS: The prevalence of PE in patients with ischemic stroke with suspected cardiogenic etiology is low. This study does not support a significant association between PE and cardiogenic ischemic stroke.[1]

References

Prevalence of pulmonary embolism in patients with suspected cardioembolic ischemic stroke. Sipola, P., Hedman, M., Jäkälä, P., Karjalainen, A.M., Peuhkurinen, K., Manninen, H., Vanninen, R. J. Thorac. Imaging (2011) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.