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Galland, F. et al.

Restriction and complexity of Mcf2 proto-oncogene expression.

MCF2/ DBL is an X-linked proto-oncogene encoding a protein with a yet undetermined function. It can be activated in vitro by loss of 5' sequences in NIH3T3 bioassays; in vivo, deletion of the gene has been found in some hemophilia B patients. PCR analysis of its expression in mouse tissues shows a restriction to the gonads and tissues of neuroectodermal origin. It also identifies an exon encoding 42 amino acids that is alternatively spliced in murine, but not human testis.[1]

References

Restriction and complexity of Mcf2 proto-oncogene expression. Galland, F., Pirisi, V., de Lapeyriere, O., Birnbaum, D. Oncogene (1991) [Pubmed]

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