The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

SBD, a novel structural subunit of the Drosophila nicotinic acetylcholine receptor, shares its genomic localization with two alpha-subunits.

Nicotinic acetylcholine receptors (nAChRs) display marked heterogeneity in both vertebrates and invertebrates. Here we describe the structure of a cDNA from Drosophila melanogaster which encodes a novel nAChR beta-type subunit (SBD or beta 2). The deduced amino acid sequence of SBD displays remarkable similarity to the Drosophila alpha-subunits, ALS and SAD, while homology to the Drosophila beta-subunit ARD is less pronounced. The temporal expression of sbd transcripts during Drosophila development is similar to that of other nAChR subunit mRNAs, with high levels being found during late embryonic and late pupal stages. In embryos, sbd and als transcripts are localized in the central nervous system. The sbd gene maps cytogenetically in proximity to the als and sad genes at position 96A of chromosome 3R, suggesting the existence of a nAChR gene cluster in invertebrates.[1]

References

  1. SBD, a novel structural subunit of the Drosophila nicotinic acetylcholine receptor, shares its genomic localization with two alpha-subunits. Sawruk, E., Udri, C., Betz, H., Schmitt, B. FEBS Lett. (1990) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities