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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Tissue specificity in expression and alternative RNA splicing of human phosphofructokinase-M and -L genes.

Mode of the expression of phosphofructokinase (PFK) -M and -L genes was examined in various human tissues including muscle, placenta, liver, kidney, pancreas, stomach and reticulocytes. The gross level of mRNA expression of PFK-M and -L genes was estimated by Northern analysis. Polymerase chain reaction was used to detect mRNA expressed at low levels in these tissues. Tissue-specific expression of alternatively spliced PFK-M gene transcripts was also determined by polymerase chain reaction. The results indicated that alternative splicing of PFK-M gene transcripts was controlled in a tissue-specific manner.[1]

References

  1. Tissue specificity in expression and alternative RNA splicing of human phosphofructokinase-M and -L genes. Nakajima, H., Kono, N., Yamasaki, T., Hamaguchi, T., Hotta, K., Kuwajima, M., Noguchi, T., Tanaka, T., Tarui, S. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
 
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