- Randomized, controlled trial of a 10-day course of amifloxacin versus trimethoprim-sulfamethoxazole in the treatment of acute, uncomplicated urinary tract infection. Amifloxacin Multi-Center Trial Group. Boyko, E.J., Iravani, A., Silverman, M.H., Schelling, D.J., Wright, R.A. Antimicrob. Agents Chemother. (1990)