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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Transcortin and alpha 2u-globulin messenger RNA activities during turpentine-induced inflammation in the rat.

Previously we have shown that the serum concentration of transcortin and alpha 2u-globulin markedly decreases during turpentine-induced inflammation. In the present study transcortin and alpha 2u-globulin mRNA from healthy rats and from animals with inflammation was translated in a rabbit reticulocyte lysate system. Female rats had higher levels of translatable transcortin mRNA than male animals and the level of mRNA for transcortin and alpha 2u-globulin decreased rapidly during inflammation. These results indicate that the sex difference in the serum level of transcortin and the changes in serum transcortin and alpha 2u-globulin during inflammation are mainly determined by differences in the mRNAs in the liver.[1]

References

  1. Transcortin and alpha 2u-globulin messenger RNA activities during turpentine-induced inflammation in the rat. Faict, D., Verhoeven, G., Mertens, B., De Moor, P. J. Steroid Biochem. (1985) [Pubmed]
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