- Structural and catalytic role of arginine 88 in Escherichia coli adenylate kinase as evidenced by chemical modification and site-directed mutagenesis. Reinstein, J., Gilles, A.M., Rose, T., Wittinghofer, A., Saint Girons, I., Bârzu, O., Surewicz, W.K., Mantsch, H.H. J. Biol. Chem. (1989)