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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Hamster placental lactogen-II contains a structural feature unique among the growth hormone-prolactin-placental lactogen family.

Sequence analysis of cDNA for hamster placental lactogen-II (PL-II) revealed that while this protein has a high degree of sequence homology to mouse and rat PL-II it contains a pair of cysteine residues not present in the mouse and rat proteins or in any other known member of the GH- PRL- PL protein family. This unique pair of cysteine residues may be responsible for the extreme tendency of hamster PL-II, compared to other members of the GH- PRL- PL family, to form disulfide-bonded hormone-serum protein complexes.[1]

References

  1. Hamster placental lactogen-II contains a structural feature unique among the growth hormone-prolactin-placental lactogen family. Southard, J.N., Do, L., Smith, W.C., Talamantes, F. Mol. Endocrinol. (1989) [Pubmed]
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