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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Vitamin K-dependent carboxylase: partial purification of the enzyme by antibody affinity techniques.

The vitamin K-dependent carboxylase activity of bovine liver microsomes has been purified 500-fold by adsorption to an antiprothrombin column and elution with a dodeca peptide which competes with a prothrombin precursor enzyme recognition site. The purified enzyme is devoid of bound precursors, and has the same ratio of vitamin K epoxidase activity to carboxylase activity as the crude microsomal preparation.[1]

References

  1. Vitamin K-dependent carboxylase: partial purification of the enzyme by antibody affinity techniques. Harbeck, M.C., Cheung, A.Y., Suttie, J.W. Thromb. Res. (1989) [Pubmed]
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