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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Newly recovered and delineated microbial species of the human genital tract.

Several new genitourinary Bacteroides species and the new Mobiluncus/Falcivibrio have been described since 1977. The normal vaginal flora consists mainly of lactobacilli and other "non-pathogenic" aerobes and anaerobes. Under unknown circumstances, organisms may increase in number, displacing the normal lactobacillus flora and raising the vaginal pH. This renders a more favourable biotope for organisms with a pH optimum in the neutral or alkaline range. Overgrowth of Gardnerella, Bacteroides, B-streptococci and Mobiluncus/Falcivibrio is indicative of vaginosis, which is not a typical sexual disease, but may be sexually transmitted. Proper treatment includes the male partner. No overall-valid therapy exists, but metronidazole is the drug of choice if Bacteroides or Gardnerella form the disturbed flora, and beta-lactams are the drugs of choice when Mobiluncus or aerobes are involved.[1]

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