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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Use of hamster hepatocytes to metabolize carcinogens in an in vitro bioassay.

Adult Syrian golden hamster hepatocytes were shown to have a high capacity to metabolize carcinogens, such as diethylnitrosamine, 2-nitrofluorene, and 4-aminoazobenzene, to a form that transforms mammalian cells. The addition of hepatocytes to the hamster embryo cell transformation system extends its range of usefulness for detecting carcinogens that require metabolic activation.[1]

References

  1. Use of hamster hepatocytes to metabolize carcinogens in an in vitro bioassay. Poiley, J.A., Raineri, R., Pienta, R.J. J. Natl. Cancer Inst. (1979) [Pubmed]
 
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