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Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36.

A gene for tRNAGlu has been assigned to human chromosome 1p36 by in situ hybridisation using a [3H]-labelled or biotinylated 2.4-kb (human) DNA fragment containing a tRNAGlu gene as a probe. With the biotinylated DNA probe a secondary statistically significant site of hybridisation was observed at 1q21-22 which might represent a pseudogene or related sequence. In fibroblasts from gorilla (Gorilla gorilla) using biotin labelling, a single site of hybridisation occurred at 1qter which provides further support for homology of 1q in the higher apes and human 1p.[1]

References

  1. Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36. Boyd, E., Theriault, A., Goddard, J.P., Kalaitsidaki, M., Spathas, D.H., Connor, J.M. Hum. Genet. (1989) [Pubmed]
 
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