- Putative metabolites derived from dietary combinations of calcium glucarate and N-(4-hydroxyphenyl)retinamide act synergistically to inhibit the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene. Abou-Issa, H.M., Duruibe, V.A., Minton, J.P., Larroya, S., Dwivedi, C., Webb, T.E. Proc. Natl. Acad. Sci. U.S.A. (1988)