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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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In vitro efficacy of sulbactam combined with ampicillin against anaerobic bacteria.

An ampicillin-sulbactam combination was compared with ampicillin alone, chloramphenicol, clindamycin, and metronidazole against 272 strains of anaerobic bacteria. Chloramphenicol and ampicillin-sulbactam were the most effective, inhibiting 98 to 99% of strains tested at breakpoint (16 micrograms/ml). The combination of sulbactam and ampicillin was much more effective than ampicillin alone against Bacteroides fragilis strains but did not differ substantially from ampicillin alone against Fusobacterium spp., gram-positive rods, and gram-positive cocci.[1]

References

  1. In vitro efficacy of sulbactam combined with ampicillin against anaerobic bacteria. Wexler, H.M., Harris, B., Carter, W.T., Finegold, S.M. Antimicrob. Agents Chemother. (1985) [Pubmed]
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