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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Granulocyte transfusions in recovery of neutropenic rats from induced E. coli toxicemia.

Rats made transiently neutropenic by intra-arterial administration of vinblastine (3 mg/kg) and infected with E. coli (6.02+/-0.45 X 10(8), per animal) have a mortality rate of 90% within 48 h post infection. Multiple transfusions of large numbers of granulocytes (harvested from Deca-Durabolin treated donor rats) protected the neutropenic animals from sepsis. Out of a group of 11 rats, 10 recovered completely after repeated granulocyte transfusions.[1]

References

  1. Granulocyte transfusions in recovery of neutropenic rats from induced E. coli toxicemia. Popovic, V., Schaffer, R., Popovic, P. Exp. Hematol. (1977) [Pubmed]
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