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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Identification of an interleukin HP1-like plasmacytoma growth factor produced by L cells in response to viral infection.

We have recently purified and partially sequenced a new T cell-derived lymphokine with growth factor activity for B cell hybridomas and plasmacytomas, which we named interleukin HP1 ( HP1). Here we show that, in response to viral infection or after treatment with poly(rI).poly(rC), L cells produce a factor that is capable of supporting the in vitro growth and survival of HP1-dependent cell lines. Serologic and structural evidence is presented in favor of the identity between the fibroblast factor and HP1, demonstrating that non-T cells can make HP1-related molecules.[1]

References

  1. Identification of an interleukin HP1-like plasmacytoma growth factor produced by L cells in response to viral infection. Cayphas, S., Van Damme, J., Vink, A., Simpson, R.J., Billiau, A., Van Snick, J. J. Immunol. (1987) [Pubmed]
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