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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Treatment of coexistent night-terrors and somnambulism in adults with imipramine and diazepam.

Night-terrors and somnambulism are comparatively rare in adults and are most often associated with stage 4 sleep, especially delta activity. Although the data are limited, reports suggest that imipramine, which may control nocturnal enuresis, a stage 4 sleep disorder, and diazepam, which suppresses stage 4 sleep, may effectively treat the condition. This paper describes two patients with night-terrors and somnambulism who responded to imipramine but not to diazepam. Possible mechanisms of diazepam and imipramine, including effects on stage 4 sleep and pervasive anxiolytic actions, are discussed.[1]

References

  1. Treatment of coexistent night-terrors and somnambulism in adults with imipramine and diazepam. Cooper, A.J. The Journal of clinical psychiatry. (1987) [Pubmed]
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