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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

A pilot study of BW A515U (6-deoxyacyclovir) in chronic hepatitis B virus infection.

BW A515U (6-Deoxyacyclovir) is a pro-drug of acyclovir and almost 100% is absorbed orally. 250 mg orally 6-hourly for 10 days was given to 4 hepatitis B surface antigen/e antigen-positive carriers. No consistent effect on productive viral replication, as determined by serum DNA polymerase and DNA levels was observed. The changes that occurred in these markers and transaminases in 1 patient were attributed to a spontaneous depression of productive viral replication.[1]

References

  1. A pilot study of BW A515U (6-deoxyacyclovir) in chronic hepatitis B virus infection. Weller, I.V., Tedder, R.S., Karayiannis, P., Thomas, H.C., Fiddian, A.P. J. Hepatol. (1986) [Pubmed]
 
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