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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Angiotensin binding sites in bovine and human retinal blood vessels.

Blood vessels isolated from bovine and human retinas have sites that specifically bind 3H-angiotensin II (3H-Ag II) with an apparent dissociation constant (Kd) of 14 nM and a capacity of binding (Bmax) of 0.82 pmol/g. The binding sites for 3H-Ag II appear to be influenced by guanine nucleotides (GTP) and cations (Mg2+ and Na+) in a way that resembles angiotensin II receptors in other tissues. The physiologic effect of blood-borne or locally-formed angiotensin II on retinal blood flow remains to be defined.[1]

References

  1. Angiotensin binding sites in bovine and human retinal blood vessels. Ferrari-Dileo, G., Davis, E.B., Anderson, D.R. Invest. Ophthalmol. Vis. Sci. (1987) [Pubmed]
 
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