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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Beam, T.R. et al.

Aztreonam concentrations in human tissues obtained during thoracic and gynecologic surgery.

The concentrations of aztreonam in human tissues obtained during surgery were measured after a single 2-g intravenous dose. The average concentration in the skeletal muscle, atrial appendage, lung, sternum, pericardial fluid, endometrium, myometrium, fallopian tube, and ovary varied from 3 to 33 micrograms/g (or microgram/ml). These concentrations significantly exceed the MIC for 90% of strains for most members of the family Enterobacteriaceae.[1]

References

Aztreonam concentrations in human tissues obtained during thoracic and gynecologic surgery. Beam, T.R., Galask, R.P., Friedhoff, L.T., Platt, T.B., Leitz, M.A. Antimicrob. Agents Chemother. (1986) [Pubmed]

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