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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Pharmacokinetics of dibekacin in children with cystic fibrosis.

Dosages and pharmacokinetics of dibekacin were studied in a group of 15 children with cystic fibrosis ( CF) and a control group of 9 children. The mean dosage regimens of dibekacin were respectively equal to 2.19 mg/kg and 2.16 mg/kg in the CF and non- CF patients. The mean peak serum values for the CF and non- CF groups were respectively equal to 5.3 micrograms/ml. Comparison of pharmacokinetic parameters (i.e. half-life, distribution volume, total body clearance and area under the curve) showed no significant difference between the two groups (p greater than 0.05).[1]

References

  1. Pharmacokinetics of dibekacin in children with cystic fibrosis. Courcol, R.J., Loeuille, G.A., Delnatte, J., Martin, G.R. International journal of clinical pharmacology research. (1985) [Pubmed]
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