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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Proton gradient-coupled uphill transport of glycylsarcosine in rabbit renal brush-border membrane vesicles.

An inward-directed proton gradient energizes the transport of intact glycylsarcosine against a concentration gradient in rabbit renal brush-border membrane vesicles. Dissipation of the proton gradient abolishes the uphill transport. Generation of an inside-negative membrane potential nearly doubles the intravesicular concentration of the dipeptide at the peak of the overshoot without altering the equilibrium value. These data provide direct evidence for peptide-proton cotransport in the renal brush-border membrane.[1]

References

  1. Proton gradient-coupled uphill transport of glycylsarcosine in rabbit renal brush-border membrane vesicles. Miyamoto, Y., Ganapathy, V., Leibach, F.H. Biochem. Biophys. Res. Commun. (1985) [Pubmed]
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