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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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A microbiological in-use comparison of surgical hand-washing agents.

Seven different surgical hand-scrub agents (one triclosan compound, two hexachlorophene compounds, and four iodophors) were evaluated under in-use conditions by five persons for efficacy in degerming the hands and forearms prior to performing a total of 215 total hip arthroplasties. With all of the compounds tested there was a significant reduction (p less than or equal to 0.001) of indigenous skin microflora from prescrub levels at both the post-scrub and postoperative points. The two hexachlorophene compounds in general revealed a bacteriostatic effect whereas the triclosan compound and the four iodophors did not. A hexachlorophene compound applied as a foam demonstrated excellent bacteriocidal and bacteriostatic action, was less time-consuming and easier to use than compounds applied as scrubs, and did not alter a low (0.47 per cent) in-use infection rate over a period of three years.[1]

References

  1. A microbiological in-use comparison of surgical hand-washing agents. Eitzen, H.E., Ritter, M.A., French, M.L., Gioe, T.J. The Journal of bone and joint surgery. American volume. (1979) [Pubmed]
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