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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Bioavailability study of gitoxin in a solid dosage form.

Although the cardiotonic activity of gitoxin is known for almost half a century, this digitalis glycoside has never been used in therapy, due to its apparent lack of resorption after administration by oral route. Recent studies have demonstrated that the bioavailability of gitoxin could be upraised to 100% provided it be given as a hydroalcoholic solution. The present paper deals with the development of a solid dosage form (tablets) using a physical association of gitoxin and sodium escinate.[1]

References

  1. Bioavailability study of gitoxin in a solid dosage form. Hupin, C., de Suray, J.M., Versluys, J., Lorent, M., Dodion, L., Lesne, M. International journal of clinical pharmacology and biopharmacy. (1979) [Pubmed]
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