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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

New esters of Halopredone for topical antiinflammatory use.

A series of new halopredone esters has been prepared and screened for local and systemic antiinflammatory activity. High local activity with no side effects, equivalent to that of 17,21-bis(acetyloxy)-2-bromo-6beta,9-difluoro-11beta-hydroxypregna-1,4-diene-3,20-dione (halopredone acetate; Topicon), is obtained when either the 17- or 21-OH of halopredone are benzoylated.[1]

References

  1. New esters of Halopredone for topical antiinflammatory use. Toscano, L., Grisanti, G., Bianchetti, A., Bossoni, G. Arzneimittel-Forschung. (1977) [Pubmed]
 
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