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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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A double-blinded comparative study of sultamicillin and potassium penicillin V in the treatment of childhood streptococcal pharyngitis.

Fifty-two children with positive pharyngeal cultures for group A streptococci were randomized to receive phenoxymethyl penicillin or sultamicillin, an ester of ampicillin and sulbactam. By serological and bacteriological criteria, sultamicillin was effective in 100% of the 20 evaluable cases of infection and carriage while penicillin was effective in six out of eight (75%) and three out of eight (93%) respectively. Of the eight children with infections treated with sultamicillin, three (37.5%) became recolonized with the organism compared to none of the children in the penicillin group. These differences were not statistically significant.[1]

References

  1. A double-blinded comparative study of sultamicillin and potassium penicillin V in the treatment of childhood streptococcal pharyngitis. Aronoff, S.C., Klinger, J.D., O'Brien, C.A., Jaffe, A.C., Blumer, J.L. J. Antimicrob. Chemother. (1984) [Pubmed]
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