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Blackburn, A.M. et al.

Effect of neurotensin on gastric function in man.

Neurotensin is a peptide recently discovered in the human ileum and it is released into plasma after ingestion of food. Neurotensin was infused intravenously into 12 healthy volunteers at a mean dose of 2.4 pmol/kg/min, the mean rise in plasma levels being 89 +/- 8 pmol/l. An inhibition of both gastric acid and pepsin output, and also a delay in gastric emptying of oral glucose, were observed. Neurotensin may therefore have a physiological role in modulating gastric function in man.[1]

References

Effect of neurotensin on gastric function in man. Blackburn, A.M., Fletcher, D.R., Bloom, S.R., Christofides, N.D., Long, R.G., Fitzpatrick, M.L., Baron, J.H. Lancet (1980) [Pubmed]

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