The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 

The control of mucin secretion into the lumen of the cat trachea by alpha- and beta-adrenoceptors, and their relative involvement during sympathetic nerve stimulation.

We have tested the effects of phenylephrine, dobutamine and salbutamol, alpha-, beta 1- and beta 2-adrenoceptor agonists respectively, on the output of radiolabelled mucins into the cat trachea in situ. Phenylephrine significantly increased mucin output, an effect inhibited by the alpha-adrenoceptor antagonists, thymoxamine or prazosin, but not by propranolol. Dobutamine increased the output of 35S-labelled mucins greatly and had a smaller effect on 3H-labelled mucins. Propranolol blocked these effects but thymoxamine did not. At high doses atenolol, a beta 1-adrenoceptor antagonist, inhibited dobutamine's effect on 35S-labelled mucins. Salbutamol caused a small increase in mucin output and propranolol blocked this increase. Electrical stimulation of the sympathetic nerve supply to the trachea increased mucin output. Propranolol inhibited this effect; thymoxamine did not. We conclude that both alpha- and beta-adrenoceptors increase mucus secretion into the cat trachea but that only the beta-adrenoceptors respond to sympathetic nerve stimulation.[1]

References

  1. The control of mucin secretion into the lumen of the cat trachea by alpha- and beta-adrenoceptors, and their relative involvement during sympathetic nerve stimulation. Peatfield, A.C., Richardson, P.S. Eur. J. Pharmacol. (1982) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities