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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Birth defects and vaginal spermicides.

In a cohort study of 50, 282 pregnancies recruited between 1958 and 1965, there were 462 gravidae who used nonmercurial spermicides (mostly nonoxynol-9 (95% confidence limits, 0.6 to 1.6). There were also 889 women who used phenylmercuric acetate (no longer available as a spermicide); the corresponding rate ratio was 0.9 (0.6 to 1.3). Limb reduction deformities, neoplasms, Down's syndrome, and hypospadias did not occur in excess in children exposed to spermicides.[1]

References

  1. Birth defects and vaginal spermicides. Shapiro, S., Slone, D., Heinonen, O.P., Kaufman, D.W., Rosenberg, L., Mitchell, A.A., Helmrich, S.P. JAMA (1982) [Pubmed]
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