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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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A comparison of a combination of penbutolol and frusemide with the two compounds individually in the treatment of hypertension.

Forty-one patients completed a randomized, double-blind, between-group comparison of a combination of penbutolol and frusemide, with penbutolol alone, and frusemide alone in the management of mild to moderate essential hypertension. The results suggest that the combination caused a superior reduction in systolic and diastolic pressure compared with penbutolol and a superior reduction in systolic blood pressure compared with frusemide.[1]

References

  1. A comparison of a combination of penbutolol and frusemide with the two compounds individually in the treatment of hypertension. Chadha, D.R., Houtzagers, J.J. British journal of clinical pharmacology. (1983) [Pubmed]
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