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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Quantitative histochemistry of the angiotensinase A ( APA) in the renal glomeruli of rats after stimulation of the renin-angiotensin system.

Quantitative histochemical measurements of aminopeptidase A ( APA, angiotensinase A) were done kinetically in the kidney glomeruli of rats after short-term experiments (treatment with furosemide as well as captopril for 2, 4, and 6 h). The APA activities increased after treatment with furosemide or captopril. Highest activities were determined after 4 h using furosemide and 6 h using captopril. It is concluded that glomerular APA activities correspond to the renin/angiotensin plasma levels and that the fast changes of APA activities are well demonstrable by kinetic densitometric measurements in situ.[1]

References

  1. Quantitative histochemistry of the angiotensinase A (APA) in the renal glomeruli of rats after stimulation of the renin-angiotensin system. Kugler, P., Schiebler, T.H. Cytometry. (1984) [Pubmed]
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