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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Abnormal cisternogram associated with Diamox therapy.

A cisternogram characteristic of normal-pressure hydrocephalus was obtained from a patient on Diamox who was being evaluated for rapid mental deterioration. A repeat cisternogram after Diamox was discontinued was nearly normal. We hypothesize that the initial abnormality resulted from reduced cerebrospinal fluid production caused by carbonic anhydrase inhibition; this defect (reduced flow) led to a net reflux of tracer into the ventricles. The reflux is believed to be due to the reduction of bulk cerebrospinal fluid from the ventricles.[1]

References

  1. Abnormal cisternogram associated with Diamox therapy. Papanicolaou, N., McNeil, B.J., Funkenstein, H.H., Sudarsky, L.R. J. Nucl. Med. (1978) [Pubmed]
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