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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Plasma beta-2-microglobulin and fibronectin levels in beta-thalassaemia.

The plasma beta 2-microglobulin (beta 2-MG) levels in 118 children with thalassaemia were investigated. The mean level was higher than in healthy children. A significant increase of beta 2-MG was associated with hypersplenism (3.14 +/- 0.6 mg/l). The beta 2-MG levels appeared to reflect reticuloendothelial system activity but were not related to iron overload. Fibronectin levels were generally lower than in healthy adults; profound chronic fibronectin depletion was not accompanied by an increased liability to infection.[1]


  1. Plasma beta-2-microglobulin and fibronectin levels in beta-thalassaemia. Cooper, E.H., Forbes, M.A., Bowen, M., Gabutti, V., Piga, A. Acta Haematol. (1984) [Pubmed]
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