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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Aminopeptidase activity in the livers of rats with experimental chronic renal failure.

Membrane-bound aminopeptidase activities in livers of rats with experimental renal failure were assayed. Only aminopeptidase A activity was decreased with the reduction in renal function, but aminopeptidase B and Leu-aminopeptidase activity did not change. The liver membrane-bound aminopeptidase A activity was inhibited by the addition of angiotensin I or -II in the enzyme assay system. From these results, it is expected that a decrease in liver membrane-bound aminopeptidase A activity may play a role in increasing angiotensin II during renal failure.[1]

References

  1. Aminopeptidase activity in the livers of rats with experimental chronic renal failure. Ogura, M., Hazato, T., Katayama, T. Biochem. Int. (1984) [Pubmed]
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