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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Urinary excretion of methylparaben and its metabolites in preterm infants.

A high-performance liquid chromatographic (HPLC) assay to quantitate methylparaben in urine was developed. Standard curves were linear and recovery of the paraben from urine averaged 82.6%. The urinary excretion of methylparaben in six preterm infants (less than or equal to 31 weeks gestational age), who were receiving intramuscular injections of a paraben-containing gentamicin formulation, ranged from 13.2 to 88.1%. Small quantities of the metabolite, p-hydroxybenzoic acid, were detected by GC-MS.[1]


  1. Urinary excretion of methylparaben and its metabolites in preterm infants. Hindmarsh, K.W., John, E., Asali, L.A., French, J.N., Williams, G.L., McBride, W.G. Journal of pharmaceutical sciences. (1983) [Pubmed]
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