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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Correction for gas compression in mechanical ventilators.

Errors in measurements arising from compression of gases in a mechanical ventilator may be corrected by calculation based on the compressible volume of the ventilator, or by physical separation of expired from compressed gases. Using a Frumin valve to effect this separation, the volume compressed in the Bear I ventilator was found to be 5.15 ml/mm Hg, and its compressible volume to be 3790 ml (range 3760 to 3806 ml). The ratio of uncorrected/corrected tidal volume (termed the correction factor) was 1.229 +/- 0.014. When VD/VT was corrected using this factor and compared with that obtained by calculating VD/VT using PECO2 measurements in expired air collected from the Frumin valve, the difference between the two was not significant. It is concluded that the use of the Frumin valve is a practical method for determining the true dead space-to-tidal volume ratios and that the application of the correction factor is also reliable.[1]

References

  1. Correction for gas compression in mechanical ventilators. Forbat, A.F., Her, C. Anesth. Analg. (1980) [Pubmed]
 
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