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Littlejohn, G.O. et al.

Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis.

The insulin response after a glucose challenge was studied in 11 male patients with diffuse idiopathic skeletal hyperostosis (DISH) and in 8 age, sex and weight matched controls. There was significant hyperinsulinemia in the DISH group, most marked at 2 h after the glucose challenge. Growth hormone levels were found to be normal in each group. The marked hyperinsulinemia in patients with DISH may play a role in the pathogenesis of this condition.[1]

References

Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis. Littlejohn, G.O., Smythe, H.A. J. Rheumatol. (1981) [Pubmed]

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