Acyclovir treatment of experimental herpetic keratitis in the rabbit eye.
In the rabbit eye model of experimental herpetic keratitis a satisfactory cure was obtained with ointments containing 1 percent, 2 percent, and 3 percent acyclovir, and also with idoxuridine. Trifluorothymidine and vidarabine were less effective in the particular conditions of the experiment. A cure was also obtained with acyclovir sodium salt injected intravenously, thus demonstrating that a local infection of the eye can be treated systematically.[1]References
- Acyclovir treatment of experimental herpetic keratitis in the rabbit eye. Bauer, D.J. Am. J. Med. (1982) [Pubmed]
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