The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 

Assignment of ADA, ITPA, AK1, and AK2 to Chinese hamster chromosomes. Genetic and structural evidence for the conservation of mammalian autosomal synteny.

Interspecific somatic cell hybrids formed by fusion of mouse Cl1D cells with Chinese hamster primary spleen or fibroblast cells were used to form a clone panel with members retaining different combinations of Chinese hamster chromosomes and isozyme markers. Concordant segregation analysis of isozymes and chromosomes among clone panel members enabled the provisional assignment of ADA, ITPA, and AK1 to Chinese hamster chromosome 6. Diphtheria toxin selection for Chinese hamster chromosome 2 segregants in Dede cell X Cl1D somatic cell hybrids indicated AK2 is located on chromosome 2. These assignments extend observations of autosomal linkage group conservation in mammals--a concept further supported by similarity of G-band patterns in certain chromosomal regions bearing homologous loci in Chinese hamsters, humans, and mice.[1]

References

  1. Assignment of ADA, ITPA, AK1, and AK2 to Chinese hamster chromosomes. Genetic and structural evidence for the conservation of mammalian autosomal synteny. Stallings, R.L., Siciliano, M.J. J. Hered. (1982) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities