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Nucleolar specific acidic phosphoprotein C23 is highly methylated.

Protein C23 (Mr = 110,000; pI, 5.5) is the major phosphoprotein in the nucleolus of Novikoff hepatoma cells and comprises 9.5% of the total nucleolar protein. In addition to being highly phosphorylated (1.2 mol % of phosphoserine), it is also highly methylated. Protein C23 contains 1.3 mol % of NG,NG-dimethylarginine and a trace of NG-monomethylarginine.[1]

References

  1. Nucleolar specific acidic phosphoprotein C23 is highly methylated. Lischwe, M.A., Roberts, K.D., Yeoman, L.C., Busch, H. J. Biol. Chem. (1982) [Pubmed]
 
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