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cDNA cloning of mouse ferredoxin reductase from kidney.

A cDNA encoding ferredoxin reductase has been isolated from a mouse kidney cDNA library using human ferredoxin reductase cDNA as a probe. Mouse ferredoxin reductase coded for 494 amino acid residues. The mouse mature enzyme which comprises 460 amino acid residues shared 87.8-89.1% amino acid identities with the bovine and human enzyme. Northern blot analysis showed that ferredoxin reductase mRNA was expressed in the adrenal, testis and ovary and to a lesser extent in the liver and kidney. However, this mRNA in the adrenal cell line, Y-1 cell, was not induced by adenosine 3',5'-cyclic monophosphate (cAMP) in contrast with ferredoxin mRNA.[1]

References

  1. cDNA cloning of mouse ferredoxin reductase from kidney. Itoh, S., Iemura, O., Yamada, E., Yoshimura, T., Tsujikawa, K., Kohama, Y., Mimura, T. Biochim. Biophys. Acta (1995) [Pubmed]
 
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