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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Control of gastric acid with high dose H2-receptor antagonists after omeprazole failure: report of two cases.

Successful omeprazole therapy in patients with symptomatic gastroesophageal reflux ( GER) refractory to treatment with H2-receptor antagonists has often been reported. In contrast, successful treatment of GER by H2-receptor antagonists in patients resistant to the acid-suppressing effects of omeprazole is rarely reported. We describe two patients who demonstrated therapeutic responses to high dose H2-receptor antagonists after high dose omeprazole failed to suppress gastric acidity and GER.[1]

References

  1. Control of gastric acid with high dose H2-receptor antagonists after omeprazole failure: report of two cases. Leite, L.P., Just, R.J., Castell, D.O., Lagerström, P.O. Am. J. Gastroenterol. (1995) [Pubmed]
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