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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The inhibitory effect of spermicidal agents on replication of HSV-2 and HIV-1 in-vitro.

Five spermicides including nonoxynol-9 were assessed under in-vitro conditions, for their inhibitory activity against two viruses capable of spread by sexual intercourse, herpes simplex virus type-2 (HSV-2) and the human immunodeficiency virus type-1. A further eight commercially-available spermicidal preparations containing varying concentrations of either nonoxynol-9 or nonoxynol-11 were also assessed for activity against HSV-2. All spermicides and spermicidal preparations tested showed inhibitory activity against both viruses over periods of time ranging from 30 sec to 5 min. This activity was dependent on the concentration of spermicide to which the viruses were exposed.[1]

References

  1. The inhibitory effect of spermicidal agents on replication of HSV-2 and HIV-1 in-vitro. Jennings, R., Clegg, A. J. Antimicrob. Chemother. (1993) [Pubmed]
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