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Human chromosome 10 loci map to three different sheep chromosomes.

The interleukin 2 receptor ( IL2RA), a human Chromosome (Chr) 10p locus, was mapped to sheep Chr 13q12-q15 by in situ hybridization. Two loci from human Chr 10q, cytochrome P450 subfamily XVII ( CYP17) and the tachykinin 2 receptor (TAC2R), were assigned to sheep Chrs 22q21-q23 and 25q14-q23 respectively. The assignment of IL2RA allows the provisional assignment of the previously unassigned sheep syntenic group U15 to sheep Chr 13. Sheep linkage group 5 is predicted to be located on sheep Chr 25 on the basis of the TAC2R assignment.[1]

References

  1. Human chromosome 10 loci map to three different sheep chromosomes. Ansari, H.A., Pearce, P.D., Maher, D.W., Broad, T.E. Mamm. Genome (1995) [Pubmed]
 
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