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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation.

Identification of a biocompatible immunoprotective membrane to prevent graft rejection remained elusive until the development of microcapsules formulated in alginate high in guluronic acid. We report insulin independence in a type 1 diabetic patient after encapsulated islet transplantation. Encapsulated human islets were injected intraperitoneally in a diabetic patient with a functioning kidney graft. Insulin independence with tight glycaemic control was demonstrated 9 months after the procedure. These results warrant a trial of a high dose of encapsulated islets in early-onset diabetic patients.[1]

References

  1. Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation. Soon-Shiong, P., Heintz, R.E., Merideth, N., Yao, Q.X., Yao, Z., Zheng, T., Murphy, M., Moloney, M.K., Schmehl, M., Harris, M. Lancet (1994) [Pubmed]
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