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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Amino acid sequence of a vitamin K-dependent Ca2+-binding peptide from bovine prothrombin.

The amino acid sequence of a 31-residue peptide from bovine prothrombin has been determined. This peptide has been shown to contain the vitamin K-dependent modification required for Ca2+ binding (Nelsestuen, G. L., and Suttie, J. W. (1973) Proc. Natl. Acad. Sci. U. S. A. 70, 3366-3370) and the modified amino acid, gamma-carboxyglutamic acid (Nelsestuen, G. L., Zytkovicz, T., and Howard, J. B. (1974) J. Biol. Chem. 249, 6347-6350). The peptide was shown to correspond to residues 12 to 42 of prothrombin.[1]

References

  1. Amino acid sequence of a vitamin K-dependent Ca2+-binding peptide from bovine prothrombin. Howard, J.B., Fausch, M.D. J. Biol. Chem. (1975) [Pubmed]
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