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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

A killed vaccine derived from the oncogenic Herpesvirus ateles.

A killed herpesvirus vaccine was prepared by inactivation of the oncogenic Herpesvirus ateles (HVA) with heat and formaldehyde. The vaccine proved safe in 9 marmosets (Saguinus oedipus) during a period of 461 days. The vaccinated marmosets developed high titers of serum antibodies against HVA and were resistant to 316 lethal dose 50 (LD50) cell-free HVA; the nonvaccinated control monkeys died of malignant lymphoma. The 5 challenged monkeys are clinically well and have now been under observation for 362 days.[1]

References

  1. A killed vaccine derived from the oncogenic Herpesvirus ateles. Laufs, R., Steinke, H. J. Natl. Cancer Inst. (1975) [Pubmed]
 
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